Product Details
Keywords
- (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone;FR 901228;Romidepsin;istodax;
- RoMidepsin/Depsipeptide(FK-228, NSC-63017);[S-(E)]-N-(3-Hydroxy-7-Mercapto-1-oxo-4- heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aMinobutanoyl-;Cyclo[(2Z)-2-aMino-2-butenoyl-L-valyl-(3S,4E)-3-hyd
- Cyclo[(2Z)-2-aMino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-Mercapto-4-heptenoyl-D-valyl-D-cysteinyl]-d8 Cyclic (35)-Disulfide
Quick Details
- ProName: (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,...
- CasNo: 128517-07-7
- Molecular Formula: C24H36N4O6S2
- Application: pharmaceutical intermediate
- PackAge: according to client's requirments
- Port: Shanghai,Tianjin, Qingdao
- ProductionCapacity: Metric Ton/Day
- Purity: 99%
- Storage: Pale Yellow Solid
- Transportation: BY AIR, BY SEA
- LimitNum: 1 Metric Ton
Superiority
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Details
Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xeno graft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.